| Round 1 | Player | Pos | School |
| 1. Carolina (2-14) | Nick Fairley | DT | AUB |
| 2. Denver (4-12) | Patrick Peterson | CB | LSU |
| 3. Buffalo (4-12) | TRADE | x | x |
trade to Cleveland
| AJ Green | WR | UGA |
| 4. Cincinnati (4-12) | Da'Quan Bowers | DE | CLEM |
| 5. Arizona (5-11) | Blaine Gabbert | QB | MIZZOU |
| 6. Cleveland (5-11) | TRADE | x | x |
trade to Buffalo (+3rd Rd Pick)
| Marcell Dareus | DL | BAMA |
| 7. San Francisco (6-10) | Ryan Mallett | QB | ARK |
| 8. Tennessee (6-10) | Von Miller | LB | TAMU |
| 9. Dallas (6-10) | Prince Amukamara | CB | NEB |
| 10. Washington (6-10) | Robert Quinn | DE | UNC |
| 11. Houston (6-10) | Aldon Smith | LB | MIZZOU |
| 12. Minnesota (6-10) | Cam Newton | QB | AUB |
| 13. Detroit (6-10) | Derek Sherrod | OT | MSU |
| 14. St. Louis (7-9) | Julio Jones | WR | BAMA |
| 15. Miami (7-9) | Mark Ingram | RB | BAMA |
| 16. Jacksonville (8-8) | Brandon Harris | CB | UM |
| 17. New England (8-8) | Ryan Kerrigan | DE | PUR |
| 18. San Diego (9-7) | Akeem Ayers | LB | UCLA |
| 19. New York Giants (10-6) | Stephen Paea | DT | ORST |
| 20. Tampa Bay (10-6) | Adrian Clayborn | DE | IOWA |
| 21. Kansas City* (10-6) | Anthony Castonzo | OT | BC |
| 22. Indianapolis* (10-6) | Nate Solder | OT | CU |
| 23. Philadelphia* (10-6) | Gabe Carimi | OT | WIS |
| 24. New Orleans* (11-5) | Aaron Williams | CB | TEX |
| 25. Seattle* (7-9) | JJ Watt | DE | WIS |
| 26. Baltimore* (12-4) | Jonathon Baldwin | WR | PIT |
| 27. Atlanta* (13-3) | Jimmy Smith | CB | CU |
| 28. New England* (14-2) | Martez Wilson | LB | ILL |
| 29. Chicago* (11-5) | Quinton Carter | FS | OKLA |
| 30. New York Jets* (11-5) | Corey Liuget | DT | ILL |
| 31. Pittsburgh* (12-4) | Mike Pouncey | OG | FLA |
| 32. Green Bay* (10-6) | Rodney Hudson | OG | FSU |
